Immune-modulatory effects of dietary Yeast Beta-1,3/1,6-D-glucan
نویسندگان
چکیده
Beta-glucans are a heterogeneous group of natural polysaccharides mostly investigated for their immunological effects. Due to the low systemic availability of oral preparations, it has been thought that only parenterally applied beta-glucans can modulate the immune system. However, several in vivo and in vitro investigations have revealed that orally applied beta-glucans also exert such effects. Various receptor interactions, explaining possible mode of actions, have been detected. The effects mainly depend on the source and structure of the beta-glucans. In the meantime, several human clinical trials with dietary insoluble yeast beta-glucans have been performed. The results confirm the previous findings of in vivo studies. The results of all studies taken together clearly indicate that oral intake of insoluble yeast beta-glucans is safe and has an immune strengthening effect.
منابع مشابه
Immune modulation by non-digestible and non-absorbable beta-1,3/1,6-glucan
Chemistry of beta-1,3/1,6-glucans Beta-glucans comprise a very diverse group of polysaccharides (even paper) in which glucose molecules as the only building block are linked together by beta-linkages. Only very few beta-glucan structures, notably beta-1,3/ 1,6-glucans, are bioactive in the sense that they interact with receptors on immune cells and elicit specific biological responses. Beta-1,3...
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